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2013 (Vol. 5, Issue: 10)
Article Information:

Effect of Different Carbon Source on Expression of Carotenogenic Genes and Astaxanthin Production in Xanthophyllomyces dendrorhous

Wei Wu and Xin Yu
Corresponding Author:  Wei Wu 

Key words:  Astaxanthin, carbon source, carotenogenic genes, Xanthophyllomyces dendrorhous, , ,
Vol. 5 , (10): 1375-1379
Submitted Accepted Published
June 25, 2013 July 10, 2013 October 05, 2013
Abstract:

The present research gives an insight into astaxanthin production, as well as transcription differences of four key carotenogenic genes, in Xanthophyllomyces dendrorhous when cultured with various carbon sources and soybean oil as co-substrates. Glucose was found to be the carbon source with best culture growth and astaxanthin production and the addition of 2% (v/v) soybean oil resulted in even higher astaxanthin producing. In addition, four carotenogenic genes encoding geranylgeranyl diphosphate synthase (crtE), phytoene desaturase (crtl), phytoene synthase lycopene cyclase(crtYB), and astaxanthin synthetase (ast), respectively, were demonstrated to be associated with different transcription levels under various substrates. The present study suggests the effectiveness of manipulating the metabolic regulation by using different carbon sources, in order to improve the production of astaxanthin.
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  Cite this Reference:
Wei Wu and Xin Yu, 2013. Effect of Different Carbon Source on Expression of Carotenogenic Genes and Astaxanthin Production in Xanthophyllomyces dendrorhous.  Advance Journal of Food Science and Technology, 5(10): 1375-1379.
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ISSN (Online):  2042-4876
ISSN (Print):   2042-4868
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