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Article Information:
Metabolism and Elimination of Oxytetracycline in Hepatopancreas of Chinese Mitten Crab Eriocheir Sinensis
Qi Feng, Quan Wang, Jianguo Wang, Yungan Zhu and Xiaojiang Chen
Corresponding Author: Xiaojiang Chen
Submitted: September 18, 2014
Accepted: October 01, 2014
Published: February 15, 2015 |
Abstract:
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The kinetic profiles of Oxytetracycline (OTC) in hepatopancreas of Eriocheir sinensis was examined in this research. The results showed that after a single-dose of 40 mg/kg body weight OTC at (18±1C) by intramuscular administration, the hepatopancreas concentration-time curve of OTC could be best described by a one-compartment model with first-order absorption and a time lag: C = 69.45×(e-0.005(t-0.0387)-e-8.195 (t-0.0387)). The elimination half-life (t1/2&beta) was 130.71 h. It is suggested that a withdrawal time of 79.51d should be required before crabs are consumed safely.
Key words: Eriocheir sinensis, metabolism, oxytetracycline, withdrawal time, , ,
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Cite this Reference:
Qi Feng, Quan Wang, Jianguo Wang, Yungan Zhu and Xiaojiang Chen, . Metabolism and Elimination of Oxytetracycline in Hepatopancreas of Chinese Mitten Crab Eriocheir Sinensis. Advance Journal of Food Science and Technology, (5): 383-387.
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ISSN (Online): 2042-4876
ISSN (Print): 2042-4868 |
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