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     Asian Journal of Medical Sciences

    Abstract
2011(Vol.3, Issue:2)
Article Information:

Serum Electrolytes and Urea Changes in P. falciparum Malarial Infected Children in Nigeria

U.E. Uzuegbu
Corresponding Author:  Uzuegbu Ugochukwu.E 
Submitted: 2010 February, 21
Accepted: 2010 September, 17
Published: 2011 April, 20
Abstract:
Malaria associated renal impairment has remained scarce in our society. Therefore, in this present study, serum electrolytes’ level and urea concentration were determined as selected renal function biomarkers in 71 malaria infected children between 0-5years receiving treatment. 67 age-matched children in apparent good health were included as control subjects. Data obtained show significant (p<0.05) increase in serum sodium and urea levels among female infected children when compared with gender-matched control but there was no demonstrated correlation between malarial parasitaemia and the changes in serum sodium or urea. Evidence indicate mild renal impairment among the malaria infected (female) children. However, it is not conclusive whether the impairment is due to the parasitaemia. Further studies are required to document the true malaria-associated renal dysfunction.

Key words:  Electrolytes, kidney, malaria, parasitaemia, urea, ,
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Cite this Reference:
U.E. Uzuegbu, . Serum Electrolytes and Urea Changes in P. falciparum Malarial Infected Children in Nigeria. Asian Journal of Medical Sciences, (2): 50-51.
ISSN (Online):  2040-8773
ISSN (Print):   2040-8765
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