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Abstract
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Article Information:
Antimicrobial Susceptibility Pattern of Urinary Tract Infection Causing Human Pathogenic Bacteria
S. Manikandan, S. Ganesapandian, Manoj Singh and A.K. Kumaraguru
Corresponding Author: S. Manikandan
Submitted: 2010 August, 30
Accepted: 2010 September, 22
Published: 2011 April, 20 |
Abstract:
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The present study aimed to ascertain the current situation of antimicrobial resistance of Urinary Tract
Infections (UTIs) caused by human pathogens. 10 midstream urine samples were collected from adult patients
were analyzed for Multidrug Resistant (MDR) strain isolation and identified. The MDR strains were identified
by the Kerby Bauer method following the definition of the National Committee of Clinical Laboratory
Standards. This result was clear that E. coli was the predominant pathogen (31.5%) causing UTI, followed by
Staphylococcus aureus (20.5%), Klebsiella pneumonia (15.8%), Proteus mirabilis (7.4%) and Pseudomonas
aeruginosa (7.5%). The percentages of resistance of all isolates to the antimicrobial agents were: 83.3% to
SXT, 80.6% to Nalidixic acid, 67.3% to Amoxycillin, 61% to Cotrimoxazole, 48.8% to Gentamycin, 46% to
ciprofloxacin and 43% to cephalexin. Isolated UTI strains were tested for susceptibility against antibiotics, few
of the antibiotics were sensitive, but most of antibiotics showed resistant to the MDR strains. Among this
E. coli, K. pneumoniae and P. aeruginosa were highly resistance to most of the antibiotics, whereas
Staphylococcus spp, and Serratia marcescens exhibited sensitive to Cephalexin, Ciprofloxacin and Gentamycin.
The present study was evaluated for the prevalence of micrograms implicated in UTI to ascertain their
antimicrobial resistance patterns and indicates emerging multidrug resistance among UTI bacterial pathogens.
Key words: Ciprofloxacin, multidrug resistant, nalidixic acid, Staphylococcus aureus, urinary tract infections, ,
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Abstract
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Cite this Reference:
S. Manikandan, S. Ganesapandian, Manoj Singh and A.K. Kumaraguru, . Antimicrobial Susceptibility Pattern of Urinary Tract Infection Causing Human Pathogenic Bacteria. Asian Journal of Medical Sciences, (2): 56-60.
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ISSN (Online): 2040-8773
ISSN (Print): 2040-8765 |
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