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Abstract
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Article Information:
Studies of the Effect of Methanolic Stem Bark Extract of Lannea acida on Fertility and Testosterone in Male Wistar Rats
M.K. Ahmed, M.A. Mabrouk, J.A. Anuka, A. Attahir, Y. Tanko, A.U. Wawata and M.S. Yusuf
Corresponding Author: M.K. Ahmed
Submitted: 2010 August, 02
Accepted: 2010 September, 17
Published: 2010 December, 24 |
Abstract:
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Objective of the study is to investigate the effect of methanolic stem bark extract of lannaeacida on
sperm count, sperm motility, sperm morphology, serum testosterone, and histology of the testes on male Wister
rats. The fresh stem bark of lanneaacida was collected from Ahmadu Bello University main campus the plant
was cleaned and air dried at room temperature and then made into powder, then macerated using 70% methanol
for 24 h a total of total of 25 adult male Wistar rats weighed between 150-200 g were randomly group into 5
different groups before oral administration of the extract. At 50 mg/kg of the group treated with lanneaacida,
the sperm count is 34.00±1.87 m/mL while the sperm count in the control group has 29.00±1.78 m/mL, the
sperm motile for the extract treated groups at 100 mg/kg is 68.20±3.56, the serum testosterone level in dose of
200 mg/kg of Lanneaacidais 0.64±0.11 there was no difference statistically at p>0.05 when compared with the
control, No histological lesion was observed in all the control groups. Findings from this study shows that
administration of the stem bark extract of lanneaacida has the tendency to enhance sperm count, morphology,
motility and serum testosterone level.
Key words: Fertility, infertility, plant extract, sperm, testis, ,
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Cite this Reference:
M.K. Ahmed, M.A. Mabrouk, J.A. Anuka, A. Attahir, Y. Tanko, A.U. Wawata and M.S. Yusuf, . Studies of the Effect of Methanolic Stem Bark Extract of Lannea acida on Fertility and Testosterone in Male Wistar Rats. Asian Journal of Medical Sciences, (6): 253-258.
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ISSN (Online): 2040-8773
ISSN (Print): 2040-8765 |
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