Home           Contact us           FAQs           
     Journal Home     |     Aim & Scope    |    Author(s) Information      |     Editorial Board     |     MSP Download Statistics
2011 (Vol. 2, Issue: 3)
Article Information:

Bovine Herpesvirus-4, A Potential Cause of Mastitis in Canadian Dairy Cows

H. Ali, G.P. Keefe and A. Cepica
Corresponding Author:  Haythm Ali 

Key words:  Antibodies, BHV-4, mastitis, PCR, virus, ,
Vol. 2 , (3): 31-34
Submitted Accepted Published
2011 August, 30 2011 October, 07 2011 December, 20

Bovine herpesvirus-4 (BHV-4), genus Rhadinovirus, is a member of the family Herpesviridae, subfamily Gammaherpesvirinae with a worldwide distribution. This study was conducted to investigate the role of the virus in mastitis and/or subclinical mastitis in the Canadian dairy herds.Milk samples from 176 dairy cows were divided into 2 main groups; A contained samples with no bacterial isolates, and B containing samples either with Staphylococcus aureus or Streptococcus uberisisolates. Approximatelyninety-eight percentages of milk samples had antibodies against BHV-4. Among cows with negative bacterial milk cultures, significantly higher titres of BHV-4 antibodies were associated with samples which had high Somatic Cell Counts (SCC), compared to low SCC samples. Viral DNA was detected in 2% of milks samples by the PCR amplification of BHV-4 glycoprotein-B gene. To our knowledge, this is the first report of the presence of BHV-4 in milk of Canadian dairy herds. Further investigation is needed to determine whether BHV-4 is one of primary causative agents in bovine mastitis, or whether the observed correlation of high titres of specific milk BHV-4 antibody with high SCC was due to reactivation of latent BHV-4 infections by primary bacterial insults.
Abstract PDF HTML
  Cite this Reference:
H. Ali, G.P. Keefe and A. Cepica, 2011. Bovine Herpesvirus-4, A Potential Cause of Mastitis in Canadian Dairy Cows.  British Journal of Dairy Sciences, 2(3): 31-34.
    Advertise with us
ISSN (Online):  2044-2440
ISSN (Print):   2044-2432
Submit Manuscript
   Current Information
   Sales & Services
Home  |  Contact us  |  About us  |  Privacy Policy
Copyright © 2015. MAXWELL Scientific Publication Corp., All rights reserved