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     British Journal of Pharmacology and Toxicology

    Abstract
2010(Vol.1, Issue:2)
Article Information:

Comparative Analysis of Chlorhexidine Gluconate, Povidone Iodine and Chloroxylenol as Scrubbing Solution

A.S. Yakubu, A.A. Abubakar, M.D. Salihu, A. Jibril and I. Isah
Corresponding Author:  Mohammed Danlami Salihu 
Submitted: 2010 May, 20
Accepted: 2010 August, 21
Published: 2010 November, 15
Abstract:
The study was carried out to determine the efficacy of stock concentration of the commonly used disinfectant as scrub solution for surgical site in goats. The evaluation of efficacy and safety of commercially available disinfectant and antiseptic (0.3% Chlorhexidine gluconate, 0.4% Chloroxylenol and 4% Povidone iodine) as scrub solution for surgical site, using stock concentration was assessed in thirty (30) Red Sokoto goats undergoing non elective surgical procedures at Usmanu Danfodiyo University, Veterinary Teaching Hospital and Zonal Veterinary Clinic, Sokoto. Colony counting was used to quantify skin bacteria Colony Forming Unit (CFU) at surgical site before and after skin preparation. Reduction of CFU before and after preparation was significant with all the three disinfectants compared (p<0.05) and the result shows that Povidone iodine and Chloroxylenol to be less effecacious than Chlorhexidine gluconate when mean colony forming unit after two minute of preparing the surgical sites.

Key words:  Chlorhexidine gluconate, chloroxylenol, povidone iodine, red sokoto goat, scrubbing solution, surgical site,
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Cite this Reference:
A.S. Yakubu, A.A. Abubakar, M.D. Salihu, A. Jibril and I. Isah, . Comparative Analysis of Chlorhexidine Gluconate, Povidone Iodine and Chloroxylenol as Scrubbing Solution. British Journal of Pharmacology and Toxicology, (2): 93-95.
ISSN (Online):  2044-2467
ISSN (Print):   2044-2459
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