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2011 (Vol. 3, Issue: 3)
Article Information:

Protective Effect of Scoparia dulcis on Brain and Erythrocytes

Ahmed Y. Coulibaly, Pierre A.E.D. Sombie, André Tibiri, Martin Kiendrebeogo, Moussa M.Y. Compaore and Odile G. Nacoulma
Corresponding Author:  COULIBALY Y. Ahmed 

Key words:  Acetylcholineterase, brain, erythrocytes, lipid peroxidation, Scoparia dulcis, ,
Vol. 3 , (3): 254-261
Submitted Accepted Published
2011 February, 08 2011 March, 08 2011 May, 05
Abstract:

In order to evaluate the protective effect of Scoparia dulcis L. (Scrophulariaceae), a medicinal plant known to have medico-magic power, different extracts were prepared by successive extraction with hexane (HE), chloroform (CE) and methanol (ME) and by a soaking in acetone (80%). These extracts were checked for their protective role against neuroinflammation and erythrocytes haemolysis. They exhibited a significant neuroprotective effect on both brain neuronal cells and neurotransmitter enzyme as acetylcholinesterase. By their cytoprotective ability the extracts prevented rat erythrocytes haemolysis between 56% and 83% at 300 :g/mL. These observed protective effects were related to the extracts antioxidant components.
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  Cite this Reference:
Ahmed Y. Coulibaly, Pierre A.E.D. Sombie, André Tibiri, Martin Kiendrebeogo, Moussa M.Y. Compaore and Odile G. Nacoulma, 2011. Protective Effect of Scoparia dulcis on Brain and Erythrocytes.  Current Research Journal of Biological Sciences, 3(3): 254-261.
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ISSN (Online):  2041-0778
ISSN (Print):   2041-076X
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