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    Abstract
2009 (Vol. 1, Issue: 3)
Article Information:

Antimicrobial Activity of the Crude Extracts of Compound Ascidians, Didemnum candidum and Didemnum psammathodes (Tunicata: Didemnidae) from Mandapam (South East Coast of India)

S. Mohamed Hussain and G. Ananthan
Corresponding Author:  Mohamed Hussain 

Key words:  Antimicrobials, cytotoxicity, marine natural products, Didemnum, tunicates, ,
Vol. 1 , (3): Page No: 168-171
Submitted Accepted Published
2009 August, 27 2009 Sept., 14
Abstract:

Many cytotoxic compounds of therapeutic interest have been isolated from marine organisms. In the present study two species of compound ascidians Didemnum psammathodes and Didemnum candidum were assayed for their antimicrobial activity against eight bacterial and four fungal pathogens. The antimicrobial activity of the crude extract of ascidian shows inhibitory activity against almost all the eight strains. However, D. psammathodes shows prominent antibacterial activity than that of Didemnum candidum. Whereas no remarkable antifungal activity was noticed against the ascidian crude extract. The maximum inhibition zone (15 mm) was observed against Salmonella typhi in the crude methanol extract of D. psammathodes and the minimum inhibition zone (1 mm) was noticed against Vibrio cholera and Staphylococcus aureas in the crude acetone extract of Didemnum candidum. In D. psammathodes the crude methanol extract the range of inhibition of the bacteria varied from 215 mm with an average of 4.3 mm. According to fungi only Aspergillus niger and Penicillium sp. were showed the trace activity against few crude extract and remaining two fungal pathogens shows negative result. In the present result two way analysis of variance was showing that there was a significant difference between the extracts as well as the strains (p<0.05).
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  Cite this Reference:
S. Mohamed Hussain and G. Ananthan, 2009. Antimicrobial Activity of the Crude Extracts of Compound Ascidians, Didemnum candidum and Didemnum psammathodes (Tunicata: Didemnidae) from Mandapam (South East Coast of India).  Current Research Journal of Biological Sciences, 1(3): Page No: 168-171.
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ISSN (Online):  2041-0778
ISSN (Print):   2041-076X
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