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2012 (Vol. 4, Issue: 1)
Article Information:

Expression Analysis of CAMP-Responsive Element Modulator Mrna in Different Tissues of Goat

Nasim Javdan and Jasem Estakhr
Corresponding Author:  Jasem Estakhr 

Key words:  CAMP-responsive element modulator, gene expression, goat, QRT-PCR, , ,
Vol. 4 , (1): 27-32
Submitted Accepted Published
2011 September, 21 2011 October, 24 2012 January, 20

CAMP-Responsive Element Modulator (CREM) is a key factor in the regulation of the expression of number of post-meiotic genes during spermatogenesis. CREM binds to transcription factor and regulates gene expression in spermatids. In the present study tissue-specific expressions of CREM and different development stage expressions of CREM in testes of goat were quantified using qRT-PCR. The highest level was detected in testes (p<0.05). The expression of CREM mRNA reached the highest level in 20-wk-old testes (p<0.05). Furthermore, immunohistochemistry localized CREM mainly expressed in round spermatids, but not in spermatogonium and spermatocyte. These results indicated that CREM was a regulation proteins and it may play an important role in spermatid maturation.
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  Cite this Reference:
Nasim Javdan and Jasem Estakhr, 2012. Expression Analysis of CAMP-Responsive Element Modulator Mrna in Different Tissues of Goat.  Current Research Journal of Biological Sciences, 4(1): 27-32.
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ISSN (Online):  2041-0778
ISSN (Print):   2041-076X
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