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2013 (Vol. 5, Issue: 3)
Article Information:

Serum Lipid Profile in Nigerian Patients with Ischaemic Cerebrovascular Accident

O.O. Festus, O.B. Idonije and H.B. Osadolor
Corresponding Author:  O.B. Idonije 

Key words:  Cerebrovascular accident, cholesterol, high density lipoprotein, lipid profile, low density lipoprotein, ,
Vol. 5 , (3): 123-125
Submitted Accepted Published
December 3, 2012 January 01, 2013 May 20, 2013
Abstract:

Ischaemic Cerebrovascular Accident (CVA) has been shown to be associated with abnormal lipid profile (dyslipidaemia) as a risk factor. There is paucity of data regarding this in this environment hence this study. In this study, a total number of 63 subjects were recruited comprised of 33 patients with cerebrovascular accident (stroke) and 30 apparently healthy volunteers as control. A complete lipid profile which included Total serum Cholesterol (TC), serum Triglyceride (TG), High Density Lipoprotein cholesterol (HDL-c) and Low Density Lipoprotein cholesterol (LDL-c) were assayed for both patients and controls. The lipid profile was determined using standard methods. The TC for both patients and control were 21253 and 19646 mg/dL respectively, TG for both patients and controls were 1599 and 7913 mg/dL respectively, HDL-c was 559 mg/dL for patients and 617 mg/dL for controls and LDL-c was 15134 mg/dL for patients and 11751 mg/dL for control subjects. TC, TG and LDL-c were higher in the ischaemic CVA patients than the controls; however only TG showed a significant increase while HDL-c although not significant was lower than control. The study therefore showed that ischaemic CVA is associated with hypercholesterolaemia, hypertriglyceridaemia and high LDL-cholesterol. We thus suggest preventive and management strategies that will reduce lipid levels (TC, TG and LDL) and enhance HDL-cholesterol in Nigeria patients that are prone to or diagnosed of ischaemic CVA.
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  Cite this Reference:
O.O. Festus, O.B. Idonije and H.B. Osadolor, 2013. Serum Lipid Profile in Nigerian Patients with Ischaemic Cerebrovascular Accident.  Current Research Journal of Biological Sciences, 5(3): 123-125.
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ISSN (Online):  2041-0778
ISSN (Print):   2041-076X
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