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2014 (Vol. 6, Issue: 2)
Article Information:

Cytotoxic Effects of (5) Medicinal Plants on Mitosis in Allium cepa Root Tips

I.J. Udo, G.A. Akpan and I.K. Esenowo
Corresponding Author:  I.K. Esenowo 

Key words:  Alcohol, Allium cepa, cytotoxic effect, mitosis, , ,
Vol. 6 , (2): 71-75
Submitted Accepted Published
September 04, 2013 September 14, 2013 March 20, 2014

The study was conducted to investigate the effects that plant extracts from 5 medicinal plants may have on mitosis in Allium cepa. Root of A .cepa were immersed in alcoholic extracts at the concentrations of 0, 25, 50, 75 and 100 mg/mL, respectively for each of the following plants: Gnetum africanum Welw., Lasianther aafricana P. Beauv, Ocimum gratissimum Linn., Telfairia occidentalis Hook F. and Vernonia amygdalina Del. Leafy vegetable which are commonly used in herbal medicine. Results obtained show that the various concentrations of the extracts from test plants had toxic effects on the cells, which caused significant reduction (p<0.05) in the mitotic index when compared with the control. Other effects were prophase inhibition, the delay of mitosis and nuclear lesion. The cytotoxic effect makes a case for a precaution in the use of the leafy extracts in herbal medicine practice.
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  Cite this Reference:
I.J. Udo, G.A. Akpan and I.K. Esenowo, 2014. Cytotoxic Effects of (5) Medicinal Plants on Mitosis in Allium cepa Root Tips.  Current Research Journal of Biological Sciences, 6(2): 71-75.
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ISSN (Online):  2041-0778
ISSN (Print):   2041-076X
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