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Abstract
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Article Information:
Biological Aging: From the Boolean Networks, To the Geometric Phase
J. Barragán and S. Sánchez
Corresponding Author: J. Barragán
Submitted: December 26, 2014
Accepted: January 27, 2015
Published: July 20, 2015 |
Abstract:
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The objective of the study is to verify the possible relationship of the basal metabolic rate according to dry weight (BMR/dry kg.), with the capacity to generate body mass (estimated as delta dry weight or DDW) and with generated body mass (estimated as dry weight or DW). The findings are analyzed within a theoretical framework of random Boolean networks and the concept of the geometric phase applied to living beings considered as systems. No significant relationship was found between the BMR/dry kg. and the DDW, so aging cannot be attributed to the continued declining of the BMR/dry kg. In contrast, a high correlation between the BMR/dry kg. and the DW was found. Such a correlation could contribute to the explanation regarding the gradual loss of homeostasis that occurs in aging. Random Boolean networks of the NK2 type may help explain the origin of homeostasis and self-organization, but they cannot explain the gradual loss during the process of aging. Applying the concept of the geometric phase could contribute to the explanation since cycle after cycle the variables do not regain the original values and the system declines.
Key words: Body mass, basal metabolism rate, homeostasis, self-organization, , ,
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Cite this Reference:
J. Barragán and S. Sánchez, . Biological Aging: From the Boolean Networks, To the Geometric Phase . Current Research Journal of Biological Sciences, (3): 47-52.
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ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
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