|
Abstract
|
Article Information:
In vitro Differentiation Mode of Pancreatic Cells into Multiple Neuronal Phenotypes
Tao Zhang
Corresponding Author: Tao Zhang
Submitted: 2010 September, 25
Accepted: 2010 October, 19
Published: 2010 November, 25 |
Abstract:
|
The in vitro differentiation features of HPNE cells into neural cells were investigated. In this study,
HPNE cells were pre-cultured in defined medium, and then induced by ITS treatment (insulin-transferrinselenium).
After a transient ductal stage, HPNE cells present neural cell morphology. A series of neural markers
were detected in terminally transformed HPNE cells. During HPNE transdifferentiation, the components of
Notch signaling were elaborately modulated. These findings indicate that HPNE cells have the differentiation
potential into neural cells.
Key words: HPNE cells, in vitro differentiation model, ITS treatment, neural, , ,
|
|
Abstract
|
PDF
|
HTML |
|
Cite this Reference:
Tao Zhang, . In vitro Differentiation Mode of Pancreatic Cells into Multiple Neuronal Phenotypes. Current Research Journal of Biological Sciences, (6): 402-406.
|
|
|
|
 |
ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
 |
| Information |
|
|
|
|
| Sales & Services |
|
|
|
|
