Home           Contact us           FAQs           
 
   Journal Page   |   Aims & Scope   |   Author Guideline   |   Editorial Board   |   Search
    Abstract
2012 (Vol. 4, Issue: 4)
Article Information:

Anti-Diabetic Activity of Cynanchum acutum Extract in Alloxan-Induced Diabetic Rats

Jasem Estakhr, Fereshteh Javadian, Zohre Ganjali, Mehdi Dehghani and Abbas Heidari
Corresponding Author:  Jasem Estakhr 

Key words:  Anti-diabetic activity, alloxan-induced diabetic rat, Cynanchum acutum, , , ,
Vol. 4 , (4): 303-305
Submitted Accepted Published
June 20, 2012 July 28, 2012 August 20, 2012
Abstract:

The present study investigates the anti-diabetic potential of Cynanchum acutum extract in alloxaninduced diabetic rats. The effects of an ethanolic extract of Cynanchum acutum on serum glucose, total cholesterol, triglycerides, plasma insulin and liver glycogen were examined in control and experimental groups. Cynanchum acutum extract reduced the serum glucose concentration at 24, 48 and 72 h. To verify the activity sub-chronically, the extract administered orally in the doses of 25, 50 and 100 mg/kg to diabetic rats for 30 days, that significantly reduced the level of glucose, total cholesterol and triglycerides with an increase in insulin and glycogen concentration to near normal levels in a dose-dependent manner. The results indicate that Cynanchum acutum extract possess anti-diabetic potential in alloxan-induced diabetic rats.
Abstract PDF HTML
  Cite this Reference:
Jasem Estakhr, Fereshteh Javadian, Zohre Ganjali, Mehdi Dehghani and Abbas Heidari, 2012. Anti-Diabetic Activity of Cynanchum acutum Extract in Alloxan-Induced Diabetic Rats.  International Journal of Animal and Veterinary Advances, 4(4): 303-305.
    Advertise with us
 
ISSN (Online):  2041-2908
ISSN (Print):   2041-2894
Submit Manuscript
   Current Information
   Sales & Services
   Contact Information
  Executive Managing Editor
  Email: admin@maxwellsci.com
  Publishing Editor
  Email: support@maxwellsci.com
  Account Manager
  Email: faisalm@maxwellsci.com
  Journal Editor
  Email: admin@maxwellsci.com
  Press Department
  Email: press@maxwellsci.com
Home  |  Contact us  |  About us  |  Privacy Policy
Copyright © 2009. MAXWELL Science Publication, a division of MAXWELLl Scientific Organization. All rights reserved