| Abstract |
Article Information:
Stability of Passive Immunisation and Efficacy of Vaccines of Hepatitis B Model
A.A. Momoh, M.O. Ibrahim and B.A. Madu
Corresponding Author: Abdulfatai Atte Momoh
Key words: Equilibrium state, epidemic, Hepatitis B, immunisation, passive, stability, vaccines Vol. 3 , (3): 107-110 |
| Submitted |
Accepted |
Published |
| 2011 June, 21 |
2011 August, 07 |
2011 September, 25 |
The phenomenon of passive immunisation in disease control models, where a stable epidemic
equilibrium state co exist with a stable disease free equilibrium when associated eigen values are all negative,
has important implication for disease control. In this study, we modelled the effect of passive immunisation and
infectious hepatitis B treatment on the spread and control of the disease. We established the existence of
equilibrium states and analyse the disease free equilibrium for stability. It was established that λ1 = -μ, λ2 = -μ,
λ3 = -(γ + μ) and λ4 = (δB / μ) - μ hence, the disease free equilibrium state will be stable if (δB / μ) < μ i.e.,
(number of susceptible individuals produced is less than natural death rate). Thus, effort should be intensify
in increasing the duration of efficacy of the vaccines used in passive immunisation programme. |
Cite this Reference:
A.A. Momoh, M.O. Ibrahim and B.A. Madu, 2011. Stability of Passive Immunisation and Efficacy of Vaccines of Hepatitis B Model.
Research Journal of Mathematics and Statistics, 3(3): 107-110. |
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ISSN (Online): 2040-7505
ISSN (Print): 2042-2024 |
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