Abstract

The cells in natural tissues and organs have diverse shapes and arrangements in structure. The tissue engineering scaffolds which have a specific extracellular matrix structure can be prepared by electro spun fibers having a diverse arrangement in structure and thus guide adherent cells grow, proliferate and divide into the regenerative tissue or organs which have specific cell morphology and orientation structure. This study is based on a Near-Field Electros Pinning (NFES) process and uses Polyvinyl Alcohol (PVA) mixed chitosan, a non-toxic, good hydrophobic and biocompatible mixed materials, to prepare a micro/nano-fiber with controllable arrangement used in tissue engineering. The purpose of this research is the realization of getting the fiber with controllable arrangement. In this study, laboratory equipment will be built which integrates a feeding system, a high voltage electric field control system, a on-line image acquisition system and a motion control system of the collection platform. It focuses on the process parameters of the micro/nano direct writing of this material. Meanwhile, verifying the controllability of the implementation of the near-field electrospinning process for preparing composite fiber using this experiment platform.

Keywords:

Controllable, direct writing, electro spinning fibers, near-field, tissue engineering,

References

Competing interests

The authors have no competing interests.

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Copyright

The authors have no competing interests.