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Abstract
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Article Information:
Infectivity and Pathogenicity of Sokoto (Northern Nigeria) Isolate of Trypanosoma evansi in West African Dwarf Goats
C.I. Ogbaje, I.A. Lawal and O.J. Ajanusi
Corresponding Author: Christopher Igoche Ogbaje
Submitted: 2010 May, 27
Accepted: 2010 July, 04
Published: 2011 June, 10 |
Abstract:
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Based on the previous reports on the existence of variations in the infectivity and pathogenicity of
Trypanosoma evansi in the field, sixteen West African Dwarf (WAD) goats were experimentally infected (I.V)
with (2.0×106) Sokoto isolate of Trypanosoma evansi. Clinical signs, temperature, hematological, gross and
histopathological changes in responses to the experimental infection were determined in the goats. All the
infected goats developed parasitaemia 3 days post infection (dpi) with slight increase in temperature in the
infected goats, decreased mean PCV % in the infected groups to as low as 18±1.47 from 22.50±0.87. There
were leucopenia and lymphocytosis in both infected and uninfected groups. Serous atrophy of fat around the
heart and kidneys was observed in goats from two groups (A and B and a goat from group (C) revealed pale
liver. Microscopically, there were no pathological lesions in the organs of the sacrificed goats from both
infected and uninfected groups. The ability of the parasite to be infective and pathogenic to mice and rat after
serial passaging through WAD goats was also tested and proven to be infective and pathogenic. It was
discovered that the parasite disappeared from both peripheral circulation and body tissues/organs after 14 days.
It was observed that infection of WAD Goats with Trypanosoma evansi (Sokoto isolate) does not produce
noticeable clinical signs, gross and histopathological lesions and it is self-limiting.
Key words: Infection, infectivity, pathogenicity, trypanosomosis, , ,
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Cite this Reference:
C.I. Ogbaje, I.A. Lawal and O.J. Ajanusi, . Infectivity and Pathogenicity of Sokoto (Northern Nigeria) Isolate of Trypanosoma evansi in West African Dwarf Goats. International Journal of Animal and Veterinary Advances, (3): 117-124.
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ISSN (Online): 2041-2908
ISSN (Print): 2041-2894 |
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