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Abstract
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Article Information:
Plasma Vitamin C, β-Carotene, Lipids and Lipoproteins in Young Adult Smokers and Non-Smokers
M.O. Ebesunun, R.A. Adetunji and K.O. Umahoin
Corresponding Author: Maria Ebesunun
Submitted: 2011 January, 12
Accepted: 2011 February, 11
Published: 2011 April, 30 |
Abstract:
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Cigarette smoke has been implicated as a significant contributing factor in the development of
chronic diseases. The adverse effect of smoking may elicit oxidative stress. This study was designed to assess
the role of cigarette smoke on plasma vitamin C, β-carotene, lipids and lipoproteins in smokers. Sixty subjects
consisting of thirty male active smokers with mean age of 37±1.84 years and thirty male non smokers with
mean age of 34.6±2.3 years were selected for this study. The anthropometric indices and biochemical
parameters were determined using standard procedures. The result shows that body mass index (BMI) (p<0.05)
and plasma vitamin C (p<0.001) were significantly reduced in the smokers when compared with non-smokers.
The plasma Total Cholesterol (TC), High Density Lipoprotein Cholesterol (HDLC), Low Density Lipoprotein
(LDLC), Triglyceride (TG), and β-carotene were however not significantly different in smokers when compared
with non Significant decreases were obtained in BMI and plasma vitamin C (p<0.001), β-carotene (p<0.01)
Significant correlations were obtained between vitamin C and HDLC (r = 0.335, p<0.05), TC and LDLC
(r = 0.923, p<0.01), body weight and BMI (r = 0.770, p<0.05) and TG and BMI (r = 0.570, p<0.02) in the
smokers. Age was significantly correlated with TG (r = 0.601, p<0.05) and BMI (r = 0.362, p<0.01). This study
that showed that reduced plasma vitamin C is associated with smoking. Because vitamin C plays important
role in the maintenance of cellular antioxidants, active smokers should take vitamin C supplement to ameliorate
the effect of cigarette smoke on cellular antioxidants.
Key words: β-carotene, HDLC, LDLC, smokers, TC, TG, vitamin C
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Cite this Reference:
M.O. Ebesunun, R.A. Adetunji and K.O. Umahoin, . Plasma Vitamin C, β-Carotene, Lipids and Lipoproteins in Young Adult Smokers and Non-Smokers. British Journal of Pharmacology and Toxicology, (2): 71-74.
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ISSN (Online): 2044-2467
ISSN (Print): 2044-2459 |
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