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Abstract
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Article Information:
Type-2 Diabetes Mellitus and Malaria Parasitaemia: Effect on Liver Function Tests
E.J. Ikekpeazu, E.E. Neboh, I.C. Maduka, I.J. Nwagbara and M.W. Nwobodo
Corresponding Author: Ebele Joy Ikekpeazu
Submitted: 2010 July, 14
Accepted: 2010 August, 09
Published: 2010 November, 10 |
Abstract:
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Diabetes M ellitus and Malaria have continually been shown to be the major killers common in major
developing countries in spite of phenomenal progress in medical sciences. The present study is therefore aimed at
assessment of liver function in diabetic patients with malaria infection, hence finding the possible contribution of malaria
infection of some organs to the pathophysiology of diabetes mellitus. The liver function profile were estimated in a total
of 140 subjects, of which 50 were diabetic patients w ith malaria parasitaemia, 50 diabetics without malaria infection
drawn from patients attending the diabetic clinic at the University of Nigeria Teaching Hospital, UNTH, Ituku-Ozalla,
Enugu. Fifty (50) non-diabetics without m alaria and 50 non-diabetics with malaria were used as controls. All the subjects
were aged between 40-70 years old and were involved in the study. The diagnosis for malaria and diabetes mellitus were
made according to WHO guidelines. There w as no significant difference in the mean blood glucose in the diabetics with
and those without malaria. The diabetics with malaria and those without malaria showed normal liver function although
alkaline phosphatase and bilirubin were slightly raised but non-significant. Both diabetics and non-diabetics with malaria
showed slight elevation in alkaline phosphatase, suggesting that diabetics with severe malaria parasitaem ia may be at
higher risk of liver dysfunction.
Key words: Assessment, diabetic patients, enzymes, liver dysfunction, parasitaemia, ,
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Cite this Reference:
E.J. Ikekpeazu, E.E. Neboh, I.C. Maduka, I.J. Nwagbara and M.W. Nwobodo, . Type-2 Diabetes Mellitus and Malaria Parasitaemia: Effect on Liver Function Tests. Asian Journal of Medical Sciences, (5): 214-217.
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ISSN (Online): 2040-8773
ISSN (Print): 2040-8765 |
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