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Abstract
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Article Information:
New Alkaloid De-Oxypalmitine from Coscinium fenestratum
K. Talat, M. Marthanda Murthy, T. Prabhakar Rao and S.Y. Anwar
Corresponding Author: K. Talat
Submitted: February 13, 2012
Accepted: March 24, 2012
Published: June 30, 2012 |
Abstract:
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Present study is aimed at to investigate phytochemically the stem bark of Coscinium fenestratum
(family Menispermaceae) a plant popularly and commonly known as “tree turmeric” used globally in traditional
medicine to treat variety of ailments, using a standard procedure. Fractionation of its methanol extract by ethyl
acetate and chloroform and subsequent column chromatography over silica gel G (60-120) mesh size led to the
isolation of Berberine, Palmitine and Jatrorrhizine. The structure of palmitine was elucidated using 1H-NMR,
13C-NMR, FABMS and DEPT analysis and was confirmed. In addition, alkaloid Deoxypalmitine (1) was
isolated from the methanol extract of the defatted stem of the Coscinium fenestratum. The structure of the new
compound 1 was determined by means of spectral data analysis and also comparing that of reference sample
of palmitine.
Key words: 13C-NMR, 1H-NMR, Coscinium fenestratum, deoxypalmitine, DEPT, FABMS, menispermaceae
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Abstract
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Cite this Reference:
K. Talat, M. Marthanda Murthy, T. Prabhakar Rao and S.Y. Anwar, . New Alkaloid De-Oxypalmitine from Coscinium fenestratum. British Journal of Pharmacology and Toxicology, (3): 115-118.
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ISSN (Online): 2044-2467
ISSN (Print): 2044-2459 |
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