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     British Journal of Pharmacology and Toxicology

    Abstract
2010(Vol.1, Issue:2)
Article Information:

Antibacterial Potential of Macroalgae Collected from the Madappam Coast, India

N. Srivastava, K. Saurav, V. Mohanasrinivasan, K. Kannabiran and M. Singh
Corresponding Author:  Kumar Saurav 
Submitted: 2010 June, 01
Accepted: 2010 July, 30
Published: 2010 November, 15
Abstract:
In vitro antimicrobial activity of two selected marine macroalgae has been evaluated in the present research, which lies in identifying certain seaweeds whose extract can act as an alternative to commonly used antibiotics hence possessing activity against human pathogens. Extract from two species of seaweed samples namely Caulerpa racemosa and Grateloupia lithophila were collected from different locations at Gulf of Mannar, Southeast Coastal Region, M andapam, Tamil Nadu, India and w ere screened for antimicrobial activity. Extracts of Methanol, Ethanol, Butanol, Acetone, Chloroform and Dichloromethane were tested against selected human pathogens. Both the seaweeds collected had shown moderate antibacterial activity with <15 mm of zone of inhibition. Out of which only butanolic extract of has shown significant activity. Phytochemical screening revealed the presence of alkaloid and phenolic compounds in both the seaweeds whereas flavonoids and steroids were found to be present in only Caulerpa racemosa. The screening result confirms that these seaweeds can be further studied and used as possible source of antimicrobial compounds.

Key words:  Alkaloids, antimicrobial activity, flavonoids, phytochemical analysis, , ,
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Cite this Reference:
N. Srivastava, K. Saurav, V. Mohanasrinivasan, K. Kannabiran and M. Singh, . Antibacterial Potential of Macroalgae Collected from the Madappam Coast, India. British Journal of Pharmacology and Toxicology, (2): 72-76.
ISSN (Online):  2044-2467
ISSN (Print):   2044-2459
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