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Abstract
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Article Information:
Effect of Paraquat Dichloride on Some Metabolic and Enzyme Parameters of Clarias gariepinus
E.N. Ogamba, I.R. Inyang and I.K. Azuma
Corresponding Author: Emmanuel Nwabueze Ogamba
Submitted: 2010 December, 24
Accepted: 2011 February, 22
Published: 2011 May, 05 |
Abstract:
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The effects of paraquat dichloride on metabolic parameters (creatinine, albumin, total bilirubin, total
urea and total protein) in the tissue (muscle and gill) of Clarias gariepinus were determined in a toxicity test.
Juvenile C. garicipinus were exposed to varying sub-lethal concentrations of paraquat dichloride (0.05, 0.10,
0.20, 0.30 and 0.40 ppm) for four days. The results indicated a significant (p<0.05) decrease in total protein and
urea with increased concentration of the toxicant. The lowest value for total protein was recorded in the muscle
(52.7±0.02 SD) at 0.05 ppm compared to the control (55.0±0.00 SD). The gill recorded the lowest value of urea
(2.33±0.05 SD) at 0.40 ppm compared to the control (2.37±0.10 SD). The fluctuations were not significant
(p>0.05). Plasma AST values decreased as the concentration of the toxicant increased, (1.92±5.20 :/L SD being
control value against 0.93±3.55 :/L SD at 0.40ppm of toxicant). However, exposure to the herbicide did not
alter the total Bilirubin. This tends to suggest that the liver may not have been affected by the toxicant. In all,
the results indicate that the decrease in metabolite values in the muscle and gill of Clarias gariepinus could be
due to stress caused by the herbicide.
Key words: Clarias gariepinus, gill, metabolic parameters, muscle, paraguat dichloride, ,
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Cite this Reference:
E.N. Ogamba, I.R. Inyang and I.K. Azuma, . Effect of Paraquat Dichloride on Some Metabolic and Enzyme Parameters of Clarias gariepinus. Current Research Journal of Biological Sciences, (3): 186-190.
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ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
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