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Abstract
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Article Information:
In-vitro Antioxidant Studies of Various Extracts of Salvia hypoleuca
Nasim Javdan and Jasem Estakhr
Corresponding Author: Jasem Estakhr
Submitted: 2011 September, 19
Accepted: 2011 October, 15
Published: 2011 January, 12 |
Abstract:
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The present study was undertaken to determine the antioxidant activities of various extracts of whole
plant of Salvia hypoleuca in different in vitro methods. The antioxidant activity was evaluated by Total
antioxidant activity (Phosphomolybdic acid method), FRAP assay with reference standard Ascorbate and total
phenol content, respectively. The methanolic extract of Salvia hypoleuca was the most effective total
antioxidant activity among the three extracts. The IC50 values of the methanolic extract of Salvia hypoleuca
and ascorbate were found to be 160 and 410 :g/mL, respectively. The methanolic extract of Salvia hypoleuca
was found more effective in FRAP assay than that of petroleum ether and ethyl acetate extracts. But when
compare to the all the three extracts with ascorbate (standard), the methanolic extract of the Salvia hypoleuca
showed the significant result. The methanolic extract of Salvia hypoleuca contains high amount of phenolic
compounds than that of other two extracts. So, the in vitro study clearly shows that the methanolic extract of
Salvia hypoleuca has a strong antioxidant activity. This study indicated that methanolic extract of Salvia
hypoleuca comprise effective potential source of natural antioxidant, which might be helpful in preventing the
progress of various oxidative stresses.
Key words: Antioxidant activity, FRAP assay, phosphomolybdic acid method, Salvia hypoleuca, , ,
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Cite this Reference:
Nasim Javdan and Jasem Estakhr, . In-vitro Antioxidant Studies of Various Extracts of Salvia hypoleuca. Current Research Journal of Biological Sciences, (1): 23-26.
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ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
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