Abstract
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Article Information:
Seroprevalence of Peste des petits ruminants Antibodies in Sheep and Goats after Vaccination in Karamoja, Uganda: Implication on Control
P.D. Luka, J. Erume, F.N. Mwiine and C. Ayebazibwe
Corresponding Author: Frank Norbert Mwiine
Submitted: 2010 October, 20
Accepted: 2010 November, 19
Published: 2011 February, 05 |
Abstract:
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A cross sectional survey was carried out to determine the prevalence of antibodies and
seroconversion to Peste des petits ruminants virus (PPRV) in small ruminants in Karamoja region, Uganda.
This region recently experienced serious outbreaks of PPR prompting vaccination interventions. A total of 316
sera samples (210 of goats and 106 of sheep) were collected from small ruminants with history of vaccination,
no vaccination and unknown history in five districts of Karamoja region. Competitive enzyme linked immunosorbent
assay (cELISA) was performed to detect the presence of antibodies against PPRV in serum. We found
an overall PPRV specific antibody sero-conversion of 55.26% (84/152) (among Vaccinated), seroprevalence
of 11.65% (2/17) (in Unvaccinated) and 53.33% (80/150) for shoats with unknown vaccination history. Seropositivity
in sheep was 51.89% compared to goats with 57.62%. Among various age groups, 1-2 year olds
showed higher sero-positivity (68.57%). Kaabong and Moroto district had highest sero-positivity of animals
(78.33%) while Abim district had the lowest sero-positive animals (20%). From this study, it can be concluded
that the animals in the region are not fully protected and this is particularly so in districts like Abim. There is
need to find out the reasons for the poor protection levels and come up with measures to address these problems
in order to improve protection against PPR.
Key words: cELISA, control, Karamoja, PPR, sero-conversion, seroprevalence, Uganda, vaccination
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Abstract
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Cite this Reference:
P.D. Luka, J. Erume, F.N. Mwiine and C. Ayebazibwe, . Seroprevalence of Peste des petits ruminants Antibodies in Sheep and Goats after Vaccination in Karamoja, Uganda: Implication on Control. International Journal of Animal and Veterinary Advances, (1): 18-22.
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ISSN (Online): 2041-2908
ISSN (Print): 2041-2894 |
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