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Article Information:
Isolation of Steroids from Acetone Extract of Ficus iteophylla
I.A. Abdulmalik, M.I. Sule, A.M. Musa, A.H. Yaro, M.I. Abdullahi, M.F. Abdulkadir and H. Yusuf
Corresponding Author: Abdulmalik Ismail
Submitted: 2011 September, 08
Accepted: 2011 September, 30
Published: 2011 November, 25 |
Abstract:
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Two steroids were isolated from the leaves of Ficus iteophylla (Family: moraceae) a plant popularly
used in African traditional medicine to treat variety of illnesses. The leaf part of the plant was investigated
phytochemically using a standard procedure. Schematic fractionation of its ethanol extract by acetone and
methanol and subsequent column chromatography of the acetone fraction over silica gel G (60-120) mesh size
led to the isolation of 3β-cholest-5-ene-3, 23diol (1) and 24 ethyl cholest-5-ene- 3β-ol (2). The structure of
these two compounds was elucidated using 1H-NMR, 13C- NMR and DEPT analysis. To the best of our search
this is the first report on the isolation of these compounds from the leaves of Ficus iteophylla.
Key words: Ficus iteophylla, 1: H- NMR, 13: C- NMR, DEPT, 3β-cholest-5-ene-3, 23diol, 24 ethyl cholest-5-ene-3β-ol
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Cite this Reference:
I.A. Abdulmalik, M.I. Sule, A.M. Musa, A.H. Yaro, M.I. Abdullahi, M.F. Abdulkadir and H. Yusuf, . Isolation of Steroids from Acetone Extract of Ficus iteophylla. British Journal of Pharmacology and Toxicology, (5): 270-272.
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ISSN (Online): 2044-2467
ISSN (Print): 2044-2459 |
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