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Abstract
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Article Information:
Potential of Aqueous and Alcohol Extracts of Quercus infectoria, Linusm usitatissium and Cinnamomum zeylanicium as Antimicrobials and Curing of Antibiotic Resistance in E. coli
Adel K. Khder and Srwa A Muhammed
Corresponding Author: Adel Kamal Khder
Submitted: 2010 May, 06
Accepted: 2010 June, 15
Published: 2010 September, 15 |
Abstract:
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Eighty two clinical isolates were collected from Sulaymani hospitals. The isolates show resistance
to more than five antibiotics. The ethanol extracts of Quercus infectoria, Linusm usitatissium and Cinnamomum
zeylanicium were proved to be the most powerful against E. coli E45 and E62 isolates, than aqueous extracts.
The extracts exhibited most of the antibiotics activity against these two isolates irrespective of their antibiotic
resistance behaviour. A comparative evaluation of plasmid elimination from E. coli E62 clinical isolate by
sub-MIC of plant extracts showed that these extracts could cure plasmids effectively at their respective
sub-MIC concentration. Maximum plasmid cured was observed by sub-MIC of ethanol extract of C. zeylanicum
at 1100 :g/mL cured two plasmids 15 and 45 kb, followed by sub-MIC of L. usitatissimus extract at 1100
:g/mL was cured 45 kb plasmid and sub-MIC of aqueous and ethanol of Q. infectoria were cured 15 kb
plasmid from E62 isolate. Curing of plasmid DNA from E. coli isolate confirmed by determining the loss of
resistance markers in cured cultures.
Key words: Antibiotic resistance, Cinnamomum zeylanicum, E. coli, Linusm usitatissium, Quercus infectoria, ,
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Abstract
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Cite this Reference:
Adel K. Khder and Srwa A Muhammed, . Potential of Aqueous and Alcohol Extracts of Quercus infectoria, Linusm usitatissium and Cinnamomum zeylanicium as Antimicrobials and Curing of Antibiotic Resistance in E. coli. Current Research Journal of Biological Sciences, (5): Page No: 333-337.
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ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
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