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Abstract
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Article Information:
Bioactivities and Iridoid Determination of a Beverage Containing Noni, Cornelian Cherries and Olive Leaf Extract
Brett J. West, De-lu Ma, Shixin Deng, C. Jarakae Jensen and Chen X. Su
Corresponding Author: Brett J. West
Submitted: January 21, 2012
Accepted: February 08, 2012
Published: April 20, 2012 |
Abstract:
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The aim of the current study was to evaluate the iridoid content, as well as the in vitro and in vivo
bioactivities, of a beverage containing noni fruit, Cornelian cherries, and olive leaf extract (Thrive
Adaptogenics Max). The average total iridoid content of the beverage was 2.09 mg/mL. The major iridoids
present were identified as asperulosidic acid, deacetylasperulosidic acid, oleuropein, morroniside, loganic acid,
and loganin. In the 2, 2-Diphenylpicrylhydrazyl (DPPH) radical scavenging assay, remarkably high in vitro
antioxidant activity was observed, with an IC50 of 3.8 :L/mL. In vivo bioactivities were evaluated in type 2
diabetic Sprague Dawley rats. In a dose-dependent manner, Thrive Adaptogenics Max reduced abnormal weight
gain, blood glucose levels, and serum Advanced Glycation End products (AGEs), as well as improved
immunity via increased T cell counts and CD4+/CD8+ ratios. These results suggest that this blend of ingredients
is beneficial for improving and maintaining health in the general population, as well as among those with
metabolic imbalance.
Key words: Advanced glycation end products, antioxidant, cornelian cherries, iridoids, noni, olive leaf extract,
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Cite this Reference:
Brett J. West, De-lu Ma, Shixin Deng, C. Jarakae Jensen and Chen X. Su, . Bioactivities and Iridoid Determination of a Beverage Containing Noni, Cornelian Cherries and Olive Leaf Extract. Advance Journal of Food Science and Technology, (2): 91-96.
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ISSN (Online): 2042-4876
ISSN (Print): 2042-4868 |
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