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Abstract
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Article Information:
Prothrombin Time, Clothing Time, Platelet Concentration and Haematocrit During Labour and Postpartum of Women in Zaria, Northern Nigeria
K.V. Olorunshola, L.N. Achie, H.L. Malik and S. Avidime
Corresponding Author: K.V. Olorunshola
Submitted: 2011 June, 06
Accepted: 2011 August, 08
Published: 2011 August, 30 |
Abstract:
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This study was aimed at studying the influence of labour and parturition on the clotting profiles,
platelet concentration and haematocrit and causes of variations of women in Zaria, Northern Nigeria. Pregnancy
is a physiologic state t frequently complicated by thrombo-embolism and haemorrhage. Prothrombin Time (PT),
Whole blood Clothing Time (CT) Platelet Concentration and haematocrit (PCV) were measured in 50 women
in labour and within one (1) hour postpartum and compared with values in aged matched non pregnant controls.
The clothing time of 3.32±0.16 min. during labour was significantly lower than values of 5.30±0.19 and
4.56±0.15 min. obtained in control and at post partum respectively (p<0.05). Postpartum haematocrit of
26.10±0.77 and 30.14±0.60% obtained during labour were significantly lower than the PCV of 36.66±0.36%
obtained in the control non pregnant subject (p<0.001, p<0.05). Prothrombin Time (PT) of 8.30±0.15 sec
obtained during labour was significantly lower than values of 9.20±0.29 and 9.40±0.34 sec obtained in controls
and postpartum respectively (p<0.05). Platelet concentration of 214.38±21.0×109 and 217.50±12.0×109 /l within
1hr postpartum and durimg labour respectively were significantly lower than the concentration of
376.47±26.21×109/l in the control subjects. We conclude that the subjects had features of hyper-coagulation
state during labour which reversed within 1hr postpartum and the subjects were anemic postpartum. The CT
and PCV were significantly altered postpartum by parity and mode of delivery.
Key words: Clotting time, haematocrit, labour, parturition, platelet count and prothrombin time, pregnancy,
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Cite this Reference:
K.V. Olorunshola, L.N. Achie, H.L. Malik and S. Avidime, . Prothrombin Time, Clothing Time, Platelet Concentration and Haematocrit During Labour and Postpartum of Women in Zaria, Northern Nigeria. Asian Journal of Medical Sciences, (4): 170-175.
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ISSN (Online): 2040-8773
ISSN (Print): 2040-8765 |
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