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Article Information:
Antibiotic Resistance in Escherichia coli Isolated from Women Genitalia and Trend of Minimal Inhibiting Concentration in a Semi-Urban
1,2FOTSING KWETCHE Pierre René *, 1,2KOUAMOUO Jonas, 1,2MBAYA Patrick, 1,2NSANGOU Adamou, 1,2WONA Jean Pierre, 1,2KOUROUMA Kaba, 1,2SIMO Josué, 2KAMENI Julienne, 2NKAFUH Gabriel Population: Bangangté, West-Cameroon
Corresponding Author: Fotsing Kwetche Pierre René
Submitted: August 16, 2012
Accepted: September 24, 2012
Published: November 20, 2012 |
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The present survey aimed at assessing drug availability, frequencies of resistant E. coli isolated from women genitalia and Minimal Inhibiting Concentrations (MIC) of common antibiotics provided by formal and informal networks in Bangangté. Susceptibility tests were performed by disc diffusion and the MIC by agar dilution techniques. The MIC tests were conducted for tetracycline, chloramphenicol and ampicillin, on two reference strains; E. coli and S. aureus. Associations between these parameters were also evaluated. Data analysis revealed that most available antibiotics include Thrimethoprim/sulfamethoxazol 97.05%, amoxicillin 94%, ampicillin 85.29%, ciprofloxacin 70% and gentamycin 29.41%. The resistance rates associated were estimated at 82, 64, 78, 52 and 18%, respectively. In addition, antibiotics provided by informal drug-selling network displayed higher MIC values. They may represent a key driving force facilitating selection of resistant bacterial strains. These findings are evidences that antimicrobial resistance is a crucial challenging issue to address in the setting, highlighting the necessity to undertake a larger-scale survey that will help mass-education in order to discourage the current trend of antimicrobial resistance and re-orient antibiotic-based chemotherapy.
Key words: Antimicrobial, drug-selling, networks, resistance, , ,
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1,2FOTSING KWETCHE Pierre René *, 1,2KOUAMOUO Jonas, 1,2MBAYA Patrick, 1,2NSANGOU Adamou, 1,2WONA Jean Pierre, 1,2KOUROUMA Kaba, 1,2SIMO Josué, 2KAMENI Julienne, 2NKAFUH Gabriel Population: Bangangté, West-Cameroon, . Antibiotic Resistance in Escherichia coli Isolated from Women Genitalia and Trend of Minimal Inhibiting Concentration in a Semi-Urban . Current Research Journal of Biological Sciences, (6): 696-701.
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ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
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