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Abstract
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Article Information:
Determination of Nephrotoxicity and Hepatoxicity of Monosodium Glutamate (MSG) Consumption
H.M. Inuwa, V.O. Aina, Baba Gabi, I. Aim ola and Leehman Ja’afaru
Corresponding Author: H.M. Inuwa
Submitted: 2011 May, 21
Accepted: 2011 July, 02
Published: 2011 August, 05 |
Abstract:
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Investigations were conducted to determine the Nephrotoxicity and Hepatoxicity of Monosodium
Glutamata (MSG). Graded doses of monosodium glutamate were administered orally to Adult Wister rats
weighing between (160.7-238.6 g) for 28 days. Liver and Kidney function tests were carried out on the blood
serum. Monosodium glutamate elicited an increase in body weight in an ascending fashion from group B to
group D though not statistically significant (p>0.05) Biochemical parameters (Electrolytes, Urea, Creatinine,
RBC, Cholesterol and Enzymes) were not seriously affected though there were increases in the concentration
or levels of same of them. This shows that monosodium glutamate has hepatoxicity and nephrotoxicity
tendencies especially when consumed at higher concentrations.
Key words: Adult wister rats, hepatoxicity, monosodium glutamate, nephrotoxicity, serum biochemistry carcinogenic, ,
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Abstract
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Cite this Reference:
H.M. Inuwa, V.O. Aina, Baba Gabi, I. Aim ola and Leehman Ja’afaru, . Determination of Nephrotoxicity and Hepatoxicity of Monosodium Glutamate (MSG) Consumption. British Journal of Pharmacology and Toxicology, (3): 148-153.
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ISSN (Online): 2044-2467
ISSN (Print): 2044-2459 |
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