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Article Information:
Protective Effect of Scoparia dulcis on Brain and Erythrocytes
Ahmed Y. Coulibaly, Pierre A.E.D. Sombie, André Tibiri, Martin Kiendrebeogo, Moussa M.Y. Compaore and Odile G. Nacoulma
Corresponding Author: COULIBALY Y. Ahmed
Submitted: 2011 February, 08
Accepted: 2011 March, 08
Published: 2011 May, 05 |
Abstract:
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In order to evaluate the protective effect of Scoparia dulcis L. (Scrophulariaceae), a medicinal plant
known to have medico-magic power, different extracts were prepared by successive extraction with hexane
(HE), chloroform (CE) and methanol (ME) and by a soaking in acetone (80%). These extracts were checked
for their protective role against neuroinflammation and erythrocytes haemolysis. They exhibited a significant
neuroprotective effect on both brain neuronal cells and neurotransmitter enzyme as acetylcholinesterase. By
their cytoprotective ability the extracts prevented rat erythrocytes haemolysis between 56% and 83% at 300
:g/mL. These observed protective effects were related to the extracts antioxidant components.
Key words: Acetylcholineterase, brain, erythrocytes, lipid peroxidation, Scoparia dulcis, ,
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Abstract
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Cite this Reference:
Ahmed Y. Coulibaly, Pierre A.E.D. Sombie, André Tibiri, Martin Kiendrebeogo, Moussa M.Y. Compaore and Odile G. Nacoulma, . Protective Effect of Scoparia dulcis on Brain and Erythrocytes. Current Research Journal of Biological Sciences, (3): 254-261.
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ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
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