Abstract

This study explored the relaxation effect of health food on the fatigue mice after exercise and discussed the pharmacodynamics function of it by measuring loaded-swimming time of mice as well as content of serum urea, hepatic glycogen and blood lactic acid. It was found that, the loaded-swimming time of mice in experimental group was much longer than control group and the difference was statistically significant (p<0.05); the serum urea value of mice was much lower than usual after swimming (p<0.05) while the hepatic glycogen value was much higher (p<0.05); blood lactic acid value was lower than control group and it was still lower after half an hour and the difference was statistically significant (p<0.05). Compound ginseng extract can effectively prolong loaded swimming time of mice, reduce serum urea content of mice after exercise, increase hepatic glycogen reserve of mice after medication and reduce lactic acid production of mice after exercise. Therefore, fatigue relief health food like compound ginseng extract can effectively strengthen body’s adaptive capacity to exercise loads and resist fatigue.

Keywords:

Compound ginseng extract, fatigue relief effect, health food, mice, pharmacodynamics,

References

1. Carpenito, L., 1995. Nursing Diagnosis: Application to Clinical Practice. Philadelphia, Lippincott, pp: 58.
   
2. Chinese Ministry of Health, 2003. Technical Specifications of Health Food Inspection and Evaluation. Science and Technology of China Press, Beijing.
   
3. Chunzi, G. and J. Sleep, 2014. China Stat., 12: 50-51.
   
4. Defeng, Z., Q. Fenglei, W. Ru and C. Wenhe, 2012. Study of invigorating spleen and qi recipe on anti-exercise-induced fatigue. Liaoning J. Tradit. Chinese Med., 39(1): 60-62.
   
5. Deqi, S., W. Wenlei, F. Wenhui and M. Bing, 2011. Anti-fatigue ability effect study of donkey milk powder on mice. J. Xinjiang Med. Univ., 33(1): 11-15.
   
6. Huiying, R., 2012. A Relationship study on Work Stress, Dispositional Optimism, Locus of Control and Sleep Quality of College Teachers. M.Sc. Thesis, Harbin Engineering University, Harbin.
   
7. Jason, L.A., J.A. Richman, A.W. Rademaker, K.M. Jordan, A.V. Plioplys, R.R. Taylor, W. McCready, C.F. Huang and S. Plioplys, 1999. A community-based study of chronic fatigue syndrome. Arch. Int. Med., 159(18): 2129-2137.
   CrossRef    PMid:10527290    
8. Jingtao, J., 2014. Study on the concept of fatigue in traditional Chinese medicine. China Med. Herald, 11(28): 81-84.
   
9. Lecarpentier, Y., 2007. Physiological role of free radicals in skeletal muscles. J. Appl. Physiol., 103(6): 1917-1918.
   CrossRef    PMid:17916668    
10. Logan, A. and C. Wong, 2001. Chronic. Fatigue syndrome: Oxidative stress and dietary modifications. Altern. Med. Rev., 6(5): 450-459.
    PMid:11703165    
11. Orlandi, A.C., C. Ventura, A.L. Gallinaro, R.A. Costa and L.V. Lage, 2012. Improvement in pain, fatigue and subjective sleep quality through sleep hygiene tips in patients with fibromyalgia. Rev. Bras. Reumatol., 52(5): 666-678.
    
12. Porsolt, R., A. Bertin and M. Jalfre, 1977. Behavioral despair in mice: A primary screening test for antidepressants. Arch. Int. Pharmacod. T., 229(2): 327-336.
    PMid:596982    
13. Rongli, L., 2014. Analysis of Procyanidine in Health Food and its Asthenopia Relief Effect. Fujian College of Traditional Chinese Medicine, Fuzhou.
    
14. Singh, A., V. Garg, S. Gupta and S.K. Kulkarni, 2002. Role of antioxidants in chronic fatigue syndrome in mice. Indian J. Exp. Biol., 40(11): 1240-1244.
    PMid:13677625    
15. Weiping, H., Z. Xiaoyun, C. Meichun et al., 2012. Fatigue relief effect of fresh momordica grosvenori drinks. Guangxi J. Light Ind., 3: 1-2.
    
16. Xiaoyan, W., X. Weiyu and W. Xiaoyan, 2015. Treatment experience of chronic fatigue syndrome. Shaanxi J. Tradit. Chinese Med., (2): 215-216.
    

Competing interests

The authors have no competing interests.

Open Access Policy

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Copyright

The authors have no competing interests.