Abstract

The extract from Bergenia scopulosa T.P. Wang (pan long qi) was obtained with the help of methanol and tested for antibacterial activity against three bacteria through methods of inhibition zone, MIC and MBC. Then, the antibacterial mechanism of the extract was studied based on the growth curve and cell membrane permeability. The results showed that the extract of Bergenia scopulosa T.P. Wang could antagonize S. aureus, P. aeruginosa and E. coli respectively, but the inhibitory impact on S. aureus was stronger than P. aeruginosa and E. coli. The antibacterial mechanism of the extract against three pathogen is as follow: drug cause a decrease in the number of cell divisions in logarithmic phases and induce the voids of cell walls to become, thus the materials in the cell to leak out.

Keywords:

Antibacterial activity, antibacterial mechanism, Bergenia scopulosa T.P, Wang (pan long qi) extract, pathogen,

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Competing interests

The authors have no competing interests.

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