Abstract

In this study, the total flavonoids from dandelion was extracted by supercritical CO₂ and the total flavonoids content in the extract was investigated by the sodium nitrite-aluminum nitrate method with Rutin as a standard product. Single-factor experiments were carried out to map the effects of extraction pressure, temperature, time and entrainer amount on the yield of flavonoids. The orthogonal experiments on the optimum technology parameters demonstrated that the influence of the experimental conditions over the yield from high to low was: (a) pressure, (b) temperature, (c) entrainer amount, (d) time. The optimization result showed that under the conditions of 50°C, 35 MPa, 80 min and 4.0 mL/g entrainer amount, the yield of the preparative supercritical fluid extraction was 4.974%.

Keywords:

Dandelion, orthogonal design, Supercritical Fluid Extraction (SFE), total flavonoids,

References

Competing interests

The authors have no competing interests.

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Copyright

The authors have no competing interests.