Research Article | OPEN ACCESS
Antioxidant and Antitumor Effect of Different Fractions of Ethyl Acetate Part from Elaeagnus angustifolia L.
Wang Ya, Zhou Shang-Zhen, Zhao Chun-Meng, Guo Tao, Ma Jian-Ping, Zhao Ping and Ran Qiu-xiu
College of Life Science and Engineering, Lan Zhou University of Technology, Lanzhou, China
Advance Journal of Food Science and Technology 2014 5:707-710
Received: February 28, 2014 | Accepted: April 17, 2014 | Published: May 10, 2014
Abstract
To determine antitumor and antioxidant activities of the different fractions of ethyl acetate of Elaeagnus angustifolia L. extract, the MTT assay, the DPPH scavenging assay and the reducing power method were used. The results showed that as the concentration and the polarity were increasing, the antioxidant activity of the different fractions of ethyl acetate of Elaeagnus angustifolia L. extract was increased. The DPPH scavenging of the E and F fractions was 94.9%. The antitumor assay showed that the different fractions of ethyl acetate of Elaeagnus angustifolia L. exhibited the inhibition of the in vitro cultured Hela cell proliferation properties. During the first 48 h, there was a dependant relation of inhibition effect and the concentration and the polarity. The higher the concentration and the polarity, the stronger the inhibition effect was. The inhibition rate was 74.34% when the concentration of F faction was 2.5 mg/mL.
Keywords:
Antioxidant, antitumor activities, different fractions, DPPH, Elaeagnus angustifolia L, ethyl acetate part, reducing power,
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Competing interests
The authors have no competing interests.
Open Access Policy
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Copyright
The authors have no competing interests.
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