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     Asian Journal of Medical Sciences


Total Antioxidant Capacity (Tac) in Hypertensive Patients

1S.C. Onuoha, 2U.E. Uzuegbu and 2Apu Murphy
1Department of Biochemistry, University of Port Harcourt, Choba Nigeria, P.M.B. 5323, Port Harcourt, Nigeria
2Department of Medical Biochemistry, Delta State University, Abraka, Nigeria
Asian Journal of Medical Sciences  2013  2:37-40
http://dx.doi.org/10.19026/ajms.5.5355  |  © The Author(s) 2013
Received: July 17, 2012  |  Accepted: October 22, 2012  |  Published: April 25, 2013

Abstract

Hypertension has been an age long ailment that has affected the entire population of the world with its many complications. This study investigated the relationship between hypertension and TAC in different age groups. Samples were collected from Bomadi general hospital in Bomadi Local Government Area of Delta State, Nigeria and the project was also conducted there. A total of 40 consenting subject between the age of 45-65 years were randomly selected for the study of which 20 were control subjects (non-hypertensive individuals). The age groups 40-49 years in hypertensive patients and 60-69 years in normotensive individuals indicate statistical significance when compared to their corresponding age group (0.9±0.25mMol/L and 1.68±0.32Mmol/L, respectively). In hypertensive subject, male shows a statistically insignificant (p≤0.05) mean higher value than female (1.14±0.18Mmol/L) and 1.01±0.21Mmol/l, respectively) while in normotensive subjects, female shows a statistically significant (p≤0.05) mean lower value than male (1.66±0.35mMol and 1.77±0.06, respectively). Total antioxidant capacity is lower in hypertensive patients and as a result these individuals are predisposed to ills associated with reduced TAC. This includes cell damage by free radicals.

Keywords:

Antioxidant capacity, hypertensive patients, normotensive,


References


Competing interests

The authors have no competing interests.

Open Access Policy

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Copyright

The authors have no competing interests.

ISSN (Online):  2040-8773
ISSN (Print):   2040-8765
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