Abstract

Vegetables consumption has been associated with lower risk of pre eclempsia in pregnancy. The aim of this study is to determine the effect of Leptadenia hastate (Pers) Decne on some biochemical parameters in pregnant rats. Leptadenia hastate (Pers) Decne is a tropical herb widely used by pregnant women in northern Nigeria with so much nutritive and therapeutic claims attributed to it. The effect of different doses of the plant on metabolic profile of pregnant rats was determined. Results obtained showed significant decrease (p≤0.05) in Fasting Blood Sugar (FBS), Total Cholesterol (TC), Triglycerides (TG) and Low Density Lipoprotein (LDL) values. Urea, creatinine and alanine aminotransferase (ALT) levels increased significantly (p≤0.05) in a dose depended manner while aspartate aminotranferase (AST) activity showed little or no change in activity. The study proved the hypolipidemic effect of L. hastate and provided a scientific support for the ethno medical uses of L. hastate in the management of pre eclempsia in the study area.

Keywords:

Fasting blood sugar, Leptadenia hastate, lipid profile, pre eclempsia, pregnant women,

References

Competing interests

The authors have no competing interests.

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The authors have no competing interests.