Research Article | OPEN ACCESS
Rate of Oxidative Stress-Mediated Acceleration of Ageing: Relationship with Habitual Emotional Disposition and Personality Traits
1O.A.Iyamu, 2H.I. Eboreime, 3A.A. Adesina, 4W.A. Adisa, 1O.Aigbe, 5N. Akpede
1Department of medical Biochemistry,College of medicine, Ambrose Alli University, Ekpoma
2Department of Mental Health, Central Hospital, Benin city, Nigeria
3Department of Psychology, Ambrose Alli University, Ekpoma
4Department of Physiology, College of Medicine, Ambrose Alli University, Ekpoma
5Department of Community Health, Irrua Specialist Hospital, Irrua, Nigeria
British Journal of Pharmacology and Toxicology 2013 3:68-73
Received: November 12, 2012 | Accepted: February 01, 2013 | Published: June 25, 2013
Abstract
The study was set out to see if any statistically verifiable correlation exists among oxidative status, personality and rate of ageing. Appropriate measurement scales were Used To Sort 155 Volunteers Into Six Personality Trait Categories, Openness To Experience, Conscienciousness, Extroversion, Agreeableness, Neuroticism, And Psychoticism (OCEAN-P). Blood samples were collected from the volunteers for the determination of the plasma activities of two endogenous antioxidant enzymes-Superoxide Dismutase (SOD) and catalase and of two markers of oxidative damage-Malondialdehyde (MDA) and Erythrocyte Osmotic Fragility (EOF). A factor, “personality factor of Ageing (PFA) here also called the Iyamu factor of ageing named after the originator, was also obtained for each volunteer. The results show that rate of ageing is more affected by oxidative status in persons of four personality types-psychoticism, Neuroticism, Extroversion, and Agreeableness-than in consciencousness and open minded (openness to experience) persons-it also suggests that open minded persons have the slowest rate of ageing.
Keywords:
Ageing, chronological age, oxidative status, personality, stress, subjective age,
Competing interests
The authors have no competing interests.
Open Access Policy
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Copyright
The authors have no competing interests.
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ISSN (Online): 2044-2467
ISSN (Print): 2044-2459 |
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