Research Article | OPEN ACCESS
Evaluation of Acute Toxicity, Antioxidant and Antibacterial Activities of Aqueous Extracts of Leaves of Eucalyptus camaldulensis Dehnhardt (MYRTACEAE) Synonym: Eucalyptus rostrata Schelcht
Ouattara Monique Brigitte, M. Kiendrebeogo and O.G. Nacoulma
Laboratoire de Biochimie et Chimie Appliquées (LABIOCA) Universite Ouaga 1 Pr Joseph KI-ZERBO, Unite de Formation et de Recherche en Sciences de la Vie et de la Terre, département de Biochimie-Microbiologie, BP 7021 Ouagadougou 03, Burkina Faso
Current Research Journal of Biological Sciences 2019 1:1-5
Received: September 19, 2018 | Accepted: November 16, 2018 | Published: February 20, 2019
Abstract
The aim of this study is to evaluate by scientific studies, the Eucalyptus camaldulensis potentialities used in traditional medicine in Burkina Faso to treat malaria. Then, acute general toxicity, antioxidant and antibacterial activities phytochemical composition were evaluated. The leaves of Eucalyptus camaldulensis Dehnhardt (Myrtaceae) are used in Burkina Faso for the treatment of malaria and respiratory diseases. Aqueous extracts of the leaves are the form of use recommended by traditional healers. We studied the acute toxicity antioxidant activity, the antibacterial activity, the phytochemical composition of aqueous extracts of Eucalyptus camaldulensis, used everywhere in Burkina Faso. Acute toxicity was studied in NMRI strain mice. The aqueous extracts were not toxic at the maximum dose of 2000 mg/kg body weight. The extracts presented antioxidant activity with an IC50 which is 12.5 μg/mL. The extracts showed no bacterial activity on three strains of bacteria tested: Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. Phytochemicals compounds that we have identified are alkaloids, flavonoids, tannins and phenolics compounds, triterpenoids and steroids, saponosides.
Keywords:
Acute toxicity, antibacterial activity, antioxidant activity, eucalyptus camaldulensis dehnhardt, phytochemicals compounds,
Competing interests
The authors have no competing interests.
Open Access Policy
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Copyright
The authors have no competing interests.
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ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
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