Abstract

A retrospective study carried out between 2006 and 2008 to establish a genetic association between ABO blood group system and prostate cancer in selected cities of the South- South geographical region, Port Harcourt and Benin city. Data were collected from the medical record folders in University of Benin Teaching Hospital. A sample size of 120 was used and control size of 740. For the data analysis, ² test and odd ratio and confidence interval were used and the control was obtained according to date, PSA value and hospital matched. From the result, 25 patients were blood type A, 11 blood type B, 1 blood type AB and 83 were blood type O, prostate cancer case. For control, 144 patients were blood type A, 78 blood type B, 19 blood type AB and 499 were blood type O. Statistically analyzing the result, mainly for type A and O that have greater frequencies in disease than in control. For type A blood, odd ratio = 1.0894 and 95% confidence interval of (OR) = 0.5622 to 1.6516. For type O blood, odd ratio = 1.0834 and 95% confidence interval of (OR) = 0.4968 to1.500. This study will be of immense use to clinical haematologist, genetic and clinical anthropologist and medical doctors in the treatment and diagnosis of prostate cancer among the south-south Nigerian population.

Keywords:

ABO blood group, genetic association, prostate cancer,

References

Competing interests

The authors have no competing interests.

Open Access Policy

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Copyright

The authors have no competing interests.