Research Article | OPEN ACCESS
Determination of the Hypoglycemic Effect of the Flower of Tamarindus indica on Alloxan Induced Diabetic Mice
1Muhammad Yalwa Gwarzo and 2Hadiza Kabir
1Department of Medical Laboratory Science, Faculty of Medicine
2Department of Biochemistry, Faculty of Science, Bayero University Kano, PMB 3011, Kano, Nigeria
International Journal of Animal and Veterinary Advances 2014 5:139-142
Received: July 12, 2013 | Accepted: September 09, 2013 | Published: October 20, 2014
Abstract
The aim of the study was to examine whether the flower of the plant Tamarind (Tamarindus indica) can prevent alloxan induced diabetes mellitus. The mice were randomly divided into 3 groups of 3 mice each. Diabetes was induced in group 1 and 2 by Intraperitoneal (IP) injection of 180 mg alloxan/kg body weight. Group 1 was induced and treated with 10 mg/kg tamarind. Group 2 was induced (untreated) whereas Group 3 was used as a control (uninduced). Serum Glucose and Malondialdehyde (MDA) levels were determined. Tamarind flowers reduced fasting glucose level and MDA concentration significantly (p<0.05) in induced treated compared with induced untreated without regenerating the b cells. From the result obtained, it can be concluded that, tamarind flower has only hypoglycemic effect with no regeneration of b-cells on chemically induced diabetes.
Keywords:
Diabetes mellitus, hypoglycaemic effect, oxidative stress, Tamarindus indica,
Competing interests
The authors have no competing interests.
Open Access Policy
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Copyright
The authors have no competing interests.
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ISSN (Online): 2041-2908
ISSN (Print): 2041-2894 |
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