Abstract

The aim of the study was to examine whether the flower of the plant Tamarind (Tamarindus indica) can prevent alloxan induced diabetes mellitus. The mice were randomly divided into 3 groups of 3 mice each. Diabetes was induced in group 1 and 2 by Intraperitoneal (IP) injection of 180 mg alloxan/kg body weight. Group 1 was induced and treated with 10 mg/kg tamarind. Group 2 was induced (untreated) whereas Group 3 was used as a control (uninduced). Serum Glucose and Malondialdehyde (MDA) levels were determined. Tamarind flowers reduced fasting glucose level and MDA concentration significantly (p<0.05) in induced treated compared with induced untreated without regenerating the b cells. From the result obtained, it can be concluded that, tamarind flower has only hypoglycemic effect with no regeneration of b-cells on chemically induced diabetes.

Keywords:

Diabetes mellitus, hypoglycaemic effect, oxidative stress, Tamarindus indica,

References

Competing interests

The authors have no competing interests.

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The authors have no competing interests.