Research Article | OPEN ACCESS
Preprocessing Digital Retinal Images for Vessel Segmentation
1Tian-Swee, Tan, 1Nurul Emaan Ameen, 2Wan Hazabah Wan Hitam, 3Yan-Chai Hum and 4Chong-Keat Teoh
1Department of Biotechnology and Medical Engineering, Faculty of Biosciences and Medical Engineering, UniversitiTeknologi Malaysia
2Department of Ophthalmology, School of Medical Sciences, UniversitiSains Malaysia
3National R&D Center in ICT, MIMOS Berhad
4Department of Computer Science, Faculty of Computing, UniversitiTeknologi Malaysia, Malaysia
Research Journal of Applied Sciences, Engineering and Technology 2017 1:1-6
Received: May 20, 2015 | Accepted: June 19, 2015 | Published: January 15, 2017
Abstract
The information contained in the retinal vasculature is used to diagnose the onset of retinal diseases such as diabetic retinopathy. However, due to non-uniform illumination and variations in imaging modalities, the contrast between the retinal blood vessels network and the background is very low, encumbering the analysis and the diagnosis processes. This prompts the need for preprocessing digital fundus images to remove noise and improve contrast thus increasing the segmentation accuracy of the retinal vasculature. In this study, we address issues of non-uniform illumination and low contrast by developing a framework that implements shade correction, image enhancement and prepares the digital fundus images for the next stage.
Keywords:
Binary mask generation, contrast enhancement, morphological operations, retinal fundus images,
References
- Hashim, F.A., N.M. Salem and A.F. Seddik, 2013. Preprocessing of color retinal fundus images. Proceeding of Japan-Egypt International Conference on Electronics, Communications and Computers (JEC-ECC), pp: 190-193.
CrossRef
- Sun, C.C., S.J. Ruan, M.C. Shie and T.W. Pai, 2005. Dynamic contrast enhancement based on histogram specification. IEEE T. Consum. Electr., 51(4): 1300-1305.
CrossRef
- Tripathi, S., K.K. Singh, B.K. Singh and A. Mehrotra, 2013. Automatic detection of exudates in retinal fundus images using differential morphological profile. Int. J. Eng. Technol., 5(3): 2024-2029.
- Dehghani, A., H.A. Moghaddam and M.S. Moin, 2012. Optic disc localization in retinal images using histogram matching. EURASIP J. Image Video Process., 19: 1-11.
CrossRef
- Gagnon, L., M. Lalonde, M. Beaulieu and M.C. Boucher, 2001. Procedure to detect anatomical structures in optical fundus images. Proseeding of Conference on Medical Imaging 2001: Image Processing, pp: 1218-1225.
Direct Link
- Garg, R., B. Mittal and S. Garg, 2011. Histogram equalization techniques for image enhancement. IJECT, 2(1): 107-111.
Direct Link
- Goatman, K.A., A.D. Whitwam, A. Manivannan, J.A. Olson and P.F. Sharp, 2003. Colour normalisation of retinal images. Proceeding of Medical Image Understanding and Analysis, pp: 49-52.
Direct Link
-
Hani, A.F.M. and H.A. Nugroho, 2009. Model-based retinal vasculature enhancement in digital fundus image using independent component analysis. Proceeding of IEEE Symposium on Industrial Electronics and Applications (ISIEA, 2009), 1: 160-164.
Direct Link
- Hatanaka, Y., T. Nakagawa, Y. Hayashi, T. Hara and H. Fujita, 2008. Improvement of automated detection method of hemorrhages in fundus images. Proceeding of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp: 5429-5432.
CrossRef
-
Lal, S. and M. Chandra, 2014. Efficient algorithm for contrast enhancement of natural images. Int. Arab J. Inform. Technol., 11(1): 95-102.
Direct Link
- Manikantan, K., M.S. Shet, M. Patel and S. Ramachandran, 2012. DWT-based illumination normalization and feature extraction for enhanced face recognition. Int. J. Eng. Technol., 1(4): 483-504.
Direct Link
- Meier, J., R. Bock, G. Michelson, L.G. Nyúl and J. Hornegger, 2007. Effects of preprocessing eye fundus images on appearance based glaucoma classification. Proceeding of the 12th International Conference on Computer Analysis of Images and Patterns (CAIP'07), pp: 165-172.
CrossRef
- Murugan, R. and K. Reeba, 2012. An automatic screening method to detect optic disc in the retina. Int. J. Adv. Inform. Technol., 2(4): 23.
CrossRef
- Narasimhan, K., V.C. Neha and K. Vjayarekha, 2012. A review of automated diabetic retinopathy diagnosis from fundus image. J. Theore. Appl. Inform. Technol., 39(2): 225-238.
Direct Link
-
Phyo, O. and A. Khaing, 2014. Automatic detection of optic disc and blood vessels from retinal images using image processing techniques. Int. J. Res. Eng. Technol., 3(3): 300-307.
CrossRef
- Ponnaiah, G.F.M. and S.S. Baboo, 2013. Automatic optic disc detection and removal of false exudates for improving retinopathy classification accuracy. Int. J. Sci. Res. Publications (IJSRP), 3(3): 1-7.
Direct Link
- Prentašic, P., S. Loncaric, Z. Vatavuk, G. Bencic, M. Subašic, T. Petkovic, L. Dujmovic, M. Malenica-Ravlic, N. Budimlija and R. Tadic, 2013. Diabetic Retinopathy Image Database(DRiDB): A new database for diabetic retinopathy screening programs research. Proceeding of International Symposium on Image and Signal Processing Analysis (ISPA, 2013), pp: 711-716.
Direct Link
- Radha, R. and B. Lakshman, 2013. Retinal image analysis using morphological process and clustering. Signal Image Process. Int. J., 4(6): 55-69.
CrossRef
-
Rahim, H.A., A.S. Ibrahim, W.M.D.W. Zaki and A. Hussain, 2014. Methods to enhance digital fundus image for diabetic retinopathy detection. Proceeding of the IEEE 10th International Colloquium on Signal Processing and Its Applications (CSPA, 2014), pp: 221-224.
CrossRef
- Saleh, M.D. and C. Eswaran, 2012. An automated blood vessel extraction algorithm in fundus images. Proceeding of the IEEE International Conference on Bioinformatics and Biomedicine, pp: 1-5.
CrossRef
- Saravanan, V., B. Venkatalakshmi and V. Rajendran, 2013. Automated red lesion detection in diabetic retinopathy. Proceeding of the IEEE Conference on Information and Communication Technologies (ICT, 2013), pp: 236-239.
CrossRef
- Shimahara, T., T. Okatani and K. Deguchi, 2004. Contrast enhancement of fundus images using regional histograms for medical diagnosis. Proceeding of the SICE 2004 Annual Conference, 1: 650-653.
Direct Link
- Suero, A., D. Marin, M.E. Gegundez-Arias and J.M. Bravo, 2013. Locating the optic disc in retinal images using morphological techniques. Proceeding of the IWWBBIO 2013, pp: 593-600.
Direct Link
- Sumathy, B. and S. Poornachandra, 2012. Retinal blood vessel segmentation using morphological structuring element and entropy thresholding. Proceeding of 3rd International Conference on Computing Communication and Networking Technologies (ICCCNT, 2012), pp: 1-5.
CrossRef
- Thakur, N. and M. Juneja, 2014. Analysis of various techniques used for optic disc and optic cup segmentation for glaucoma diagnosis. Int. J. Adv. Res. Comput. Sci. Software Eng., 4(12): 933-936.
Direct Link
- Yi, Y. and D. Zhang, 2011. Observation model based retinal fundus image normalization and enhancement. Proceeding of the 4th International Congress on Image and Signal Processing (CISP, 2011), 2: 719-723.
CrossRef
- Youssif, A.A.A., A.Z. Ghalwash and A.S. Ghoneim, 2006. Comparative study of contrast enhancement and Illumination equalization methods for retinal vasculature segmentation. Proceeding of 3rd Cairo International Biomedical Engineering Conference, pp: 5.
Direct Link
- Youssif, A.A.A., A.Z. Ghalwash and A.S. Ghoneim, 2007. A comparative evaluation of preprocessing methods for automatic detection of retinal anatomy. Proceeding of the 5th International Conference on Informatics and Systems (INFOS'07), pp: 24-30.
Direct Link
Competing interests
The authors have no competing interests.
Open Access Policy
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
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The authors have no competing interests.
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