|
Abstract
|
Article Information:
Geometric and Histopathologic Assessment of Yarrow Extracts (Achillea millefolium) and on Healing of Experimental Skin Wounds and its Comparison with Zinc Oxide on Rats
Ali Rezaie, Daryoush Mohajeri, Mohammadreza Valilou, Ghafour Mousavi, Mehrdad Nazeri, Babak Mohammadi, and Solmaz Zakhireh
Corresponding Author: Ali Rezaie
Submitted: 2011 November, 18
Accepted: 2011 December, 20
Published: 2012 Januar, 20 |
Abstract:
|
Skin wound healing especially when it occurs on the face or somewhere important for cosmetic
reasons, is very significant physiological procedure. It is quite obvious that promoting this healing is important
too. In this study we tried to compare the effects of Achillea millefolium and Zinc oxide on secondary
intentioned open-wound healing in rats. Zinc oxide is being used worldwide as an absorbent and protective
compound. Its pharmacological properties are wide and its non-toxic material allows it to be used as a routine
skin care substance. In current study, 70 female wistar rats where included in 5 groups. Full thickness Incisional
wound with 23 mm diameter was made with surgical scissors and scalpel. The whole operation was taking
place under general Anesthesia and analgesia circumstances. After making surgical wounds, rats are treated
as mentioned in the text. Rats are observed for 28 days for wound closure process and inflammatory conditions
taking place in wound. Biopsy intervals are 0 (the day of surgery), 3, 7, 14, 21 and 28th day after surgery. In
these certain days rats were euthanized and biopsies of wound sites were obtained. Wounds areas are also
measured by Scion Image ™ software daily. At last, all data were analyzed using SPSS statistics ver.17. As
a result, Achillea millefolium at the dose of 10% has significant healing properties compared to Zinc oxide.
These data were validating under confidence surface of 95 % (p<0.01).
Key words: Achillea millefolium, healing, rats, skin wounds, zinc oxide, ,
|
|
Abstract
|
PDF
|
HTML |
|
Cite this Reference:
Ali Rezaie, Daryoush Mohajeri, Mohammadreza Valilou, Ghafour Mousavi, Mehrdad Nazeri, Babak Mohammadi, and Solmaz Zakhireh, . Geometric and Histopathologic Assessment of Yarrow Extracts (Achillea millefolium) and on Healing of Experimental Skin Wounds and its Comparison with Zinc Oxide on Rats. Current Research Journal of Biological Sciences, (1): 90-95.
|
|
|
|
 |
ISSN (Online): 2041-0778
ISSN (Print): 2041-076X |
 |
| Information |
|
|
|
|
| Sales & Services |
|
|
|
|
