Abstract

Permanent magnets are interesting for the use in magnetic drug targeting devices. The magnetic fields and forces with distances from magnets have limited the depth of targeting. Producing greater forces at deep depth by optimally designed magnet arrays would allow treatment of a wider class of patients. In this study, we present a design of a permanent magnet array for deep magnetic capture of super paramagnetic iron oxide nano-particles, which consists of an array of 3 individual bar permanent magnet positioned to achieve a reasonably magnitude magnetic field and its gradient within a deeply region. These configurations were simulated with two-dimensional finite-element methods. The super paramagnetic iron oxide nano-particles were adopted Fe3O4 particles with diameter 40 nm by chemical co-precipitation method. Performance factors were defined to relate magnetic field force with mass. The field strength and gradient were measured by a Hall probe and agreed well with the simulations.

Keywords:

Halbach-like arrays, magnetic drug targeting, magnetostatic application, super paramagnetic iron oxide nano-particles,

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Competing interests

The authors have no competing interests.

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